The clinical, laboratory and pathological features were evaluated in 44 patients with fatty liter, those were proved by needle biopsy.
The following results were obtained.
1. The mean age of the patients was 40.2±11.8 years old, and the most prevalent age group was 4th decade(40.9%). The male and female ratio was 3.4 : 1.
2. Suspected etiologies were obesity(61.4%), alcohol(18.2%), cryptogenic(13.6%), diabetes mellitus(6.8%), and prednisolon(2.3%).
3. Clinical symptoms were asymptomatic(50%), fatigue and/or weakness(43%) and anorexia etc.
4. Degrees of fatty infiltration on biopsy specimens revealed mild(18.2%) moderate(45.5%) and severe(36.4%).
5. Degrees of ultrasonographic findings(20 cases) were resemble those degrees of biopsy findings and positive rate was 80%.
6. Liver scan showed mottlings in 44% of patients and 28% of the patients had no abnormal findings.
7. HBsAb positive cases were 61.4% and no HBV markers found in 31.8% of the patients.
8. Diagnoses without liver biopsy were NANB hepatitis about half of the patients and only 20% of cases were suspected as fatty liver.
9. At the time of diagnosis, hypsrtriglyceridemias revealed at rate of 75%(30/40 cases), and the differences of the levels of serum TG, ALT and AST according to the degrees of fatty infiltration were not presented respectively.
10. The differences of the TG, ALT and AST levels between before and after treatmentwerenotedsignificantly.
11. The significant relationships between degrees of fatty liver and degrees of obesity were observed (Grade Ⅰ and Ⅱ : P<0.05, Ⅰ and Ⅲ : P<0.01).
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